mRNA structural dynamics shape Argonaute-target interactions
Ruijtenberg S*, Sonneveld S*, Cui TJ, Logister I, de Steenwinkel D, Xiao Y, MacRae IJ, Joo C, Tanenbaum ME.
Nat Struct Mol Biol. 2020; July 13. DOI: 10.1038/s41594-020-0461-1 PDF
Quantification of mRNA translation in live cells using single-molecule imaging.
Khuperkar D*, Hoek TA*, Sonneveld S, Verhagen BMP, Boersma S, Tanenbaum ME.
Nat Protoc. 2020 Apr;15(4):1371-1398. DOI: 10.1038/s41596-019-0284-x. PDF
Multi-color single-molecule imaging uncovers extensive heterogeneity in mRNA decoding
Boersma S*, Khuperkar D*, Verhagen BMP, Sonneveld S, Grimm JB, Lavis LD and Tanenbaum ME.
Cell 2019 Jul 11;178(2):458-472.e19. doi: 10.1016/j.cell.2019.05.001. PDF
Single-molecule imaging uncovers rules governing nonsense-mediated mRNA decay
Hoek TA*, Khuperkar D*, Lindeboom RGH, Sonneveld S, Verhagen BMP, Boersma S, Vermeulen M, Tanenbaum ME.
Mol Cell. 2019 Jul 25;75(2):324-339.e11. doi: 10.1016/j.molcel.2019.05.008. PDF
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
Jost M, Chen Y*, Gilbert LA*, Horlbeck MA*, Krenning L*, Menchon G*, Rai A*, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME# and Weissman JS# # Corresponding authors * Equal contributions
Mol Cell. 2017 Oct 5;68(1):210-223.e6. doi: 10.1016/j.molcel.2017.09.012. PDF
Cell scientist to watch – Marvin Tanenbaum
J Cell Sci. 2017 130: 817-818; PDF
Dynamics of Translation of Single mRNA Molecules In Vivo.
Yan X, Hoek TA, Vale RD and Tanenbaum ME.
Cell. 2016 May 5;165(4):976-89. DOI: 10.1016/j.cell.2016.04.034. PDF
Regulation of mRNA translation during mitosis.
Tanenbaum ME, Stern-Ginossar N, Weissman JS and Vale RD.
eLife. 2015 Aug 25;4:e07957. DOI: 10.7554/eLife.07957. PDF
A protein tagging system for signal amplification in gene transcription and fluorescence imaging.
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS and Vale RD.
Cell 2014 Oct 23;159(3):635-46. doi: 10.1016/j.cell.2014.09.039. PDF