Key publications
Translation and Replication Dynamics of Single RNA Viruses
Boersma S, Rabouw HH, Bruurs LJM, Pavlovič T, van Vliet ALW, Beumer J, Clevers H, van Kuppeveld FJM, Tanenbaum ME.
Cell. 2020 Dec 23; 183, 1–16. doi: 10.1016/j.cell.2020.10.019 PDF
mRNA structural dynamics shape Argonaute-target interactions
Ruijtenberg S*, Sonneveld S*, Cui TJ, Logister I, de Steenwinkel D, Xiao Y, MacRae IJ, Joo C, Tanenbaum ME.
Nat Struct Mol Biol. 2020; July 13. doi: 10.1038/s41594-020-0461-1 PDF
Quantification of mRNA translation in live cells using single-molecule imaging.
Khuperkar D*, Hoek TA*, Sonneveld S, Verhagen BMP, Boersma S, Tanenbaum ME.
Nat Protoc. 2020 Apr;15(4):1371-1398. doi: 10.1038/s41596-019-0284-x. PDF
Multi-color single-molecule imaging uncovers extensive heterogeneity in mRNA decoding
Boersma S*, Khuperkar D*, Verhagen BMP, Sonneveld S, Grimm JB, Lavis LD and Tanenbaum ME.
Cell 2019 Jul 11;178(2):458-472.e19. doi: 10.1016/j.cell.2019.05.001. PDF
Single-molecule imaging uncovers rules governing nonsense-mediated mRNA decay
Hoek TA*, Khuperkar D*, Lindeboom RGH, Sonneveld S, Verhagen BMP, Boersma S, Vermeulen M, Tanenbaum ME.
Mol Cell. 2019 Jul 25;75(2):324-339.e11. doi: 10.1016/j.molcel.2019.05.008. PDF
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
Jost M, Chen Y*, Gilbert LA*, Horlbeck MA*, Krenning L*, Menchon G*, Rai A*, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME# and Weissman JS# # Corresponding authors * Equal contributions
Mol Cell. 2017 Oct 5;68(1):210-223.e6. doi: 10.1016/j.molcel.2017.09.012. PDF
Cell scientist to watch – Marvin Tanenbaum
J Cell Sci. 2017 130: 817-818; PDF
Dynamics of Translation of Single mRNA Molecules In Vivo.
Yan X, Hoek TA, Vale RD and Tanenbaum ME.
Cell. 2016 May 5;165(4):976-89. doi: 10.1016/j.cell.2016.04.034. PDF
Regulation of mRNA translation during mitosis.
Tanenbaum ME, Stern-Ginossar N, Weissman JS and Vale RD.
eLife. 2015 Aug 25;4:e07957. doi: 10.7554/eLife.07957. PDF
A protein tagging system for signal amplification in gene transcription and fluorescence imaging.
Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS and Vale RD.
Cell 2014 Oct 23;159(3):635-46. doi: 10.1016/j.cell.2014.09.039. PDF