Key publications

Translation and Replication Dynamics of Single RNA Viruses

Boersma SRabouw HHBruurs LJMPavlovič T, van Vliet ALW, Beumer J, Clevers H, van Kuppeveld FJM, Tanenbaum ME.

Cell. 2020 Dec 23; 183, 1–16. doi: 10.1016/j.cell.2020.10.019 PDF

 

mRNA structural dynamics shape Argonaute-target interactions

Ruijtenberg S*, Sonneveld S*, Cui TJ, Logister I, de Steenwinkel D, Xiao Y, MacRae IJ, Joo C, Tanenbaum ME.

Nat Struct Mol Biol. 2020; July 13. doi: 10.1038/s41594-020-0461-1 PDF

Quantification of mRNA translation in live cells using single-molecule imaging.

Khuperkar D*, Hoek TA*, Sonneveld S, Verhagen BMP, Boersma S, Tanenbaum ME.

Nat Protoc. 2020 Apr;15(4):1371-1398. doi: 10.1038/s41596-019-0284-x. PDF

Multi-color single-molecule imaging uncovers extensive heterogeneity in mRNA decoding

Boersma S*, Khuperkar D*, Verhagen BMP, Sonneveld S, Grimm JB, Lavis LD and Tanenbaum ME.

Cell 2019 Jul 11;178(2):458-472.e19. doi: 10.1016/j.cell.2019.05.001. PDF

Single-molecule imaging uncovers rules governing nonsense-mediated mRNA decay

Hoek TA*, Khuperkar D*, Lindeboom RGH, Sonneveld S, Verhagen BMP, Boersma S, Vermeulen M, Tanenbaum ME.

Mol Cell. 2019 Jul 25;75(2):324-339.e11. doi: 10.1016/j.molcel.2019.05.008. PDF

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Jost M, Chen Y*, Gilbert LA*, Horlbeck MA*, Krenning L*, Menchon G*, Rai A*, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME# and Weissman JS#              # Corresponding authors   * Equal contributions

Mol Cell. 2017 Oct 5;68(1):210-223.e6. doi: 10.1016/j.molcel.2017.09.012. PDF

Cell scientist to watch – Marvin Tanenbaum

J Cell Sci. 2017 130: 817-818; PDF

 

Dynamics of Translation of Single mRNA Molecules In Vivo.

Yan X, Hoek TA, Vale RD and Tanenbaum ME.  

Cell. 2016 May 5;165(4):976-89. doi: 10.1016/j.cell.2016.04.034. PDF

Regulation of mRNA translation during mitosis.

Tanenbaum ME, Stern-Ginossar N, Weissman JS and Vale RD.

eLife. 2015 Aug 25;4:e07957. doi: 10.7554/eLife.07957. PDF

A protein tagging system for signal amplification in gene transcription and fluorescence imaging.

Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS and Vale RD. 

Cell 2014 Oct 23;159(3):635-46. doi: 10.1016/j.cell.2014.09.039. PDF